Role of Platelet-derived Microvesicles as Crosstalk Mediators in Atherothrombosis and Future Pharmacology Targets: a Link between Inflammation, Atherosclerosis and Thrombosis
Reports in the last decade have suggested that the role of platelets in atherosclerosis and its here thrombotic complications may be mediated, in part, by local secretion of platelet-derived microvesicles (pMVs), small cell blebs released during the platelet activation process.MVs are the most abundant cell-derived microvesicle subtype in the circu